Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing : Second Annual
نویسنده
چکیده
Because of considerable interest from Congress, the National Institutes of Health (NIH), and the public about animal welfare and alternatives to animal testing, the National Library of Medicine (NLM) searches its online databases and prepares quarterly annotated bibliographies on alternative or in vitro methods for toxicity testing and biomedical research. The objective is to present current literature organized as citations with brief annotations for easy scanning.
منابع مشابه
P. Radiosensitivity in Vitro of Human Soft Tissue Sarcoma Cell Lines and Skin Fibroblasts Derived From
The Scientific Community, concerned about animal welfare, is sensitive to concerns regarding how and why animals are used in biomedical research and testing to evaluate the toxicological potential of various substances. Although alternatives to methods based on the use of animals may not satisfy all requirements and needs of the biomedical research and toxicologic testing communities, alternati...
متن کاملReplacing Animals As Test Systems Prepared By: Toxicology and Environmental Health Information Program Specialized Information Services National Library of Medicine National Institutes of Health Bethesda, MD USA
The Scientific Community, concerned about animal welfare, is sensitive to concerns regarding how and why animals are used in biomedical research and testing to evaluate the toxicological potential of various substances. Although alternatives to methods based on the use of animals may not satisfy all requirements and needs of the biomedical research and toxicologic testing communities, alternati...
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The scientific community is sensitive to concerns about how and why animals are used in biomedical research and testing. Although alternatives to methods based on the use of animals may not satisfy all the requirements of the biomedical research communities, alternatives to the use of vertebrates have been developed and validated. Research on such methodologies is aimed at refining procedures t...
متن کاملInvertebrates in testing of environmental chemicals: are they alternatives?
An enlarged interpretation of alternatives in toxicology testing includes the replacement of one animal species with another, preferably a nonmammalian species. This paper reviews the potential of invertebrates in testing environmental chemicals and provides evidence of their usefulness in alternative testing methodologies. The first part of this review addresses the use of invertebrates in lab...
متن کاملA New Method for Characterization of Biological Particles in Microscopic Videos: Hypothesis Testing Based on a Combination of Stochastic Modeling and Graph Theory
Introduction Studying motility of biological objects is an important parameter in many biomedical processes. Therefore, automated analyzing methods via microscopic videos are becoming an important step in recent researches. Materials and Methods In the proposed method of this article, a hypothesis testing function is defined to separate biological particles from artifact and noise in captured v...
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تاریخ انتشار 2003